omegalib is a middleware designed to ease the development of applications on virtual reality and immersive systems. Its main features are:

Support for hybrid systems, presenting high definition 2d and 3d content on the same display surface
Display system scalability
Support for a wide range of input peripherals (controllers, motion capture systems, touch surfaces)
Integration with third party higher level toolkits like Unity, vtk, Open Scene Graph, Qt.
Altough omegalib is designed mostly to run on VR systems, it can be used to develop applications on standard desktop systems as well, leveraging the power of multiple Gpu units when available.